Session 1: Vineyard environment interaction. Towards an ameliorated vineyard ecosystem Environmental conditions optimal for quality wine-grape production are of a complex nature and are not easily defined. For example, a sufficient amount of radiation is required, but overexposure deteriorates yield quality. Similarly, a correct water balance is necessary for optimal grape development. The vast expansion of wine consumption worldwide and the increasing demand for quality wine, along with apparent signs of climate change and repeated droughts in many wine vineyard growing areas, make a better understanding of the vineyard-environment interactions necessary. Session 2: Physiology of stress in grapevine: challenges and solutions Farmers have selected plant materials (variety, rootstock) and viticultural practices in accordance with local climatic conditions in order to optimize yield and quality. Common practices include irrigation, fertilization, soil tillage, disease control, pruning, trellising and harvesting. These viticultural practices can be modified to adapt to climatic variability and to optimize grape yield, aroma and flavor. In recent years, strategies applied in arid land viticulture were introduced into central Europe as a means of buffering the impact of climate change. The development of ad-hoc practices is thus becoming pivotal in facing the upcoming uncertainties in relation to the environment. Session 3: High-throughput/Omics perspectives of grapevine response to stress The economic value of grape as an agricultural crop relates not only to the yield but also to the quality of the berry as reflected by its chemical composition. A fundamental strategy to ameliorate fruit quality in a changing climate by optimizing viticulture practices lies in the (i) understanding of the mechanisms modulating the molecular physiology of the vine and the grape, (ii) dissecting the regulation of polyphenol and aroma potential, and the (iii) identification of candidate gene regulators of key biochemical pathways.